Sequoia National Park is a national park of the United States in the southern Sierra Nevada east of Visalia, California.

The park is notable for its giant sequoia trees, including the General Sherman tree, the largest tree on Earth by volume. The General Sherman tree grows in the Giant Forest, which contains five of the ten largest trees in the world. The Giant Forest is connected by the Generals Highway to Kings Canyon National Park's General Grant Grove, home of the General Grant tree among other giant sequoias. The park's giant sequoia forests are part of 202,430 acres (316 sq mi; 81,921 ha; 819 km) of old-growth forests shared by Sequoia and Kings Canyon National Parks. The parks preserve a landscape that was first cultivated by the Monache tribe, the southern Sierra Nevada before Euro-American settlement.

The park was established on September 25, 1890, and today protects 404,064 acres (631 sq mi; 163,519 ha; 1,635 km) of forested mountainous terrain. Encompassing a vertical relief of nearly 13,000 feet (4,000 m), the park contains the highest point in the contiguous United States, Mount Whitney, at 14,505 feet (4,421 m) above sea level. The park is south of, and contiguous with, Kings Canyon National Park; both parks are administered by the National Park Service together as Sequoia and Kings Canyon National Parks. UNESCO designated the areas as Sequoia-Kings Canyon Biosphere Reserve in 1976.

Many park visitors enter Sequoia National Park through its southern entrance near the town of Three Rivers at Ash Mountain at 1,700 ft (520 m) elevation. The lower elevations around Ash Mountain contain the only National Park Service-protected California Foothills ecosystem, consisting of blue oak woodlands, foothills chaparral, grasslands, yucca plants, and steep, mild river valleys. Seasonal weather results in a changing landscape throughout the foothills with hot summer yielding an arid landscape while spring and winter rains result in blossoming wildflowers and lush greens. The region is also home to abundant wildlife: bobcats, foxes, ground squirrels, rattlesnakes, and mule deer are commonly seen in this area, and more rarely, reclusive mountain lions and the Pacific fisher are seen as well. The last California grizzly was killed in this park in 1922 (at Horse Corral Meadow).